3-AD® Prohormone

3-AD and TRT: Enhancing Testosterone Therapy

Testosterone Replacement Therapy (TRT) is a common approach for men with low testosterone. While effective, TRT can sometimes cause fluctuations in hormone levels and increase hematocrit, which may raise cardiovascular risk. 3-AD (Dehydroandrosterol) offers a natural, HPTA-friendly way to complement TRT, helping men maintain stable testosterone levels and overall well-being.


What is 3-AD?


3-AD is a patented compound that supports the body’s natural testosterone production. Unlike synthetic hormones, it works with the hypothalamic-pituitary-testicular axis (HPTA) to enhance testosterone levels without suppressing LH and FSH, the hormones responsible for signaling testosterone production.


How 3-AD Works with TRT


Adding 3-AD alongside TRT may provide several benefits:

  1. Slower testosterone decline after injections, potentially allowing longer intervals between shots
  2. Maintenance of hematocrit within safe ranges, reducing cardiovascular concerns
  3. Support for free, bioavailable, and total testosterone levels, improving energy, strength, and well-being

Bloodwork Results


  1. Real-world data supports the synergy of 3-AD with TRT:
  2. A TRT user taking 3-AD for six weeks saw total testosterone increase from 854 ng/dL to 1740 ng/dL
  3. Hematocrit decreased slightly from 52.8% to 51.6%, staying within a safe range
  4. Another user saw his total testosterone 1 day post injection 1121 ng/dL increase only 4.7% 5 days later to 1069 ng/dL vs 55% decline in the same dosing and injection protocol when 3-AD® was not used.
  5. Users reported increased energy, strength, and overall well-being

Why Men Choose 3-AD with TRT


Men choose 3-AD as a TRT adjunct for its HPTA-friendly profile, metabolic support, and potential to optimize therapy outcomes. Unlike some prescription options, 3-AD does not suppress the body’s natural hormone production and may help reduce the frequency of injections while keeping hematocrit stable.
Conclusion
3-AD is a practical, science-backed way to enhance TRT outcomes naturally. With bloodwork-backed efficacy, hematocrit stability, and improved energy and strength, it offers men a reliable tool to maximize the benefits of testosterone therapy safely.

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